Dr Órla Burke

PhD student

I am a Research Assistant at the Matine and Freshwater Research Centre at Atlantic Technological University, Galway on the Gill Disease of Atlantic Salmon (GIDAS) project. My current research supports the prevention of amoebic gill disease in farmed Atlantic salmon (Salmo salar) in Ireland through the production of recombinant protein and DNA vaccines. This project aims to understand gill disease epidemiology and development, with a goal to improving fish health and welfare through minimally-invasive preventative strategies.

I completed my BSc in Microbiology at National University of Ireland, Galway in 2018. I also completed my PhD in Infectious Disease Microbiology at University of Galway under the supervision of Prof. James P. O’Gara in 2025. My doctoral research focused on the function of the cryptic AdpS protein in the human opportunistic pathogen Staphylococcus epidermidis, using a variety of genetic and molecular techniques to investigate the physiological effects of adpS gene deletion on microbial metabolism and biofilm formation. I also investigated the genetic mechanisms underpinning the switch from low-level heterogeneous to high-level homogeneous β-lactam resistance in S. epidermidis.

My broader research interests include host-pathogen interactions, bacterial virulence, antimicrobial resistance, and the application of molecular biology to challenges in aquaculture health. I am particularly interested in research that connects fundamental microbiology with practical approaches to infectious disease prevention and treatment, especially strategies that promote responsible antimicrobial stewardship.

In my free time, I enjoy doing art with my friends, bouldering, reading, skiing and sea-swimming.

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The aim of this work is to develop a novel vaccine against Amoebic Gill Disease (AGD)